Annexon Inc (ANNX)

Official site

HEALTHCARE • BIOTECHNOLOGY • NASDAQ

$3.60

-0.07 (-1.91%)

Market Cap: $695.75M

Last updated: Oct 16, 2026 at 1:54 PM ET

Earnings

Performance (10Y)

Beat Rate

50%(13/26)

Avg Surprise

-208.08%

Upcoming Estimates

Period ending Sep 30, 2026

EPS Consensus$-0.28

Range$-0.31 - $-0.25

6 analysts

EPS RevisionsNo revisions (7d)

30d

EPS Estimate DriftChange to current

90d ago$-0.25-11.0%

60d ago$-0.25-10.2%

30d ago$-0.28-0.6%

7d ago$-0.280.0%

Current$-0.28

Revenue Consensus

Range$0 - $0

10 analysts

Period ending Dec 31, 2026

EPS Consensus$-0.23

Range$-0.32 - $-0.16

6 analysts

Revenue Consensus

Range$0 - $0

10 analysts

Period	Reported	Est.	Range	Surprise	B/M	Analysts	Revisions	YoY
Dec 31, 2026Dec 26EST	-	$-0.23	$-0.32 - $-0.16	-	-	6	-	-
Sep 30, 2026Sep 26EST	-	$-0.28	$-0.31 - $-0.25	-	-	6	0 5 30d	-
Jun 30, 2026Jun 26 Reported Aug 12, 2026Reported Aug 12	$-0.28	$-0.23	$-0.27 - $-0.22	-21.74%	Miss	6	4 0 30d	+17.6%
Mar 31, 2026Mar 26 Reported May 7, 2026Reported May 7	$-0.23	$-0.30	$-0.34 - $-0.26	+23.33%	Beat	6	No revisions (30d)	+37.8%
Dec 31, 2025Dec 25 Reported Mar 30, 2026Reported Mar 30	$-0.28	$-0.32	$-0.36 - $-0.29	+12.47%	Beat	6	2 2 30d	+15.2%
Sep 30, 2025Sep 25 Reported Nov 10, 2025Reported Nov 10	$-0.37	$-0.34	$-0.35 - $-0.32	-8.82%	Miss	4	4 0 30d	-48.0%
Jun 30, 2025Jun 25 Reported Aug 14, 2025Reported Aug 14	$-0.34	$-0.36	$-0.37 - $-0.35	+5.56%	Beat	4	0 3 30d	-47.8%
Mar 31, 2025Mar 25 Reported May 12, 2025Reported May 12	$-0.37	$-0.29	$-0.33 - $-0.26	-27.59%	Miss	3	No revisions (30d)	-76.2%
Dec 31, 2024Dec 24 Reported Mar 3, 2025Reported Mar 3	$-0.33	$-0.29	$-0.34 - $-0.27	-12.51%	Miss	4	3 1 30d	+8.3%
Sep 30, 2024Sep 24 Reported Nov 14, 2024Reported Nov 14	$-0.25	$-0.27	$-0.31 - $-0.25	+7.41%	Beat	4	0 3 30d	+41.9%
Jun 30, 2024Jun 24 Reported Aug 12, 2024Reported Aug 12	$-0.23	$-0.24	$-0.32 - $-0.19	+4.17%	Beat	8	No revisions (30d)	+51.1%
Mar 31, 2024Mar 24 Reported May 13, 2024Reported May 13	$-0.21	$-0.35	$-0.40 - $-0.26	+40.00%	Beat	7	No revisions (30d)	+59.6%
Dec 31, 2023Dec 23 Reported Mar 26, 2024Reported Mar 26	$-0.36	$-0.44	$-0.53 - $-0.31	+18.18%	Beat	8	3 0 30d	+25.0%
Sep 30, 2023Sep 23 Reported Nov 13, 2023Reported Nov 13	$-0.43	$-0.51	$-0.58 - $-0.44	+15.69%	Beat	8	No revisions (30d)	+15.7%
Jun 30, 2023Jun 23 Reported Aug 7, 2023Reported Aug 7	$-0.47	$-0.54	$-0.57 - $-0.50	+12.96%	Beat	8	No revisions (30d)	+51.0%
Mar 31, 2023Mar 23 Reported May 8, 2023Reported May 8	$-0.52	$-0.52	$-0.54 - $-0.50	+0.00%	Beat	6	No revisions (30d)	+43.5%
Dec 31, 2022Dec 22 Reported Mar 6, 2023Reported Mar 6	$-0.48	$-0.53	$-0.57 - $-0.49	+9.43%	Beat	8	No revisions (30d)	+50.5%
Sep 30, 2022Sep 22 Reported Nov 3, 2022Reported Nov 3	$-0.51	$-0.92	$-0.97 - $-0.71	+44.57%	Beat	8	No revisions (30d)	+45.2%
Jun 30, 2022Jun 22 Reported Aug 8, 2022Reported Aug 8	$-0.96	$-0.95	$-0.97 - $-0.90	-1.05%	Miss	6	No revisions (30d)	-17.1%
Mar 31, 2022Mar 22 Reported May 9, 2022Reported May 9	$-0.92	$-1.03	$-1.08 - $-0.92	+10.68%	Beat	6	No revisions (30d)	-35.3%
Dec 31, 2021Dec 21 Reported Mar 1, 2022Reported Mar 1	$-0.97	$-0.92	$-1.00 - $-0.81	-5.43%	Miss	6	No revisions (30d)	-59.0%
Sep 30, 2021Sep 21 Reported Nov 9, 2021Reported Nov 9	$-0.93	$-0.88	$-0.90 - $-0.86	-5.68%	Miss	5	No revisions (30d)	-60.3%
Jun 30, 2021Jun 21 Reported Aug 16, 2021Reported Aug 16	$-0.82	$-0.68	$-0.72 - $-0.62	-20.59%	Miss	4	No revisions (30d)	+97.2%
Mar 31, 2021Mar 21 Reported May 17, 2021Reported May 17	$-0.68	$-0.65	$-0.66 - $-0.52	-4.62%	Miss	4	No revisions (30d)	+79.4%
Dec 31, 2020Dec 20 Reported Mar 25, 2021Reported Mar 25	$-0.61	$-0.44	$-0.47 - $-0.42	-38.64%	Miss	3	No revisions (30d)	-916.7%
Sep 30, 2020Sep 20 Reported Nov 16, 2020Reported Nov 16	$-0.58	$-0.35	$-0.38 - $-0.31	-65.71%	Miss	3	No revisions (30d)	-1060.0%
Jun 30, 2020Jun 20 Reported Jul 24, 2020Reported Jul 24	$-28.87	$-0.53	$-0.62 - $-0.37	-5347.17%	Miss	3	No revisions (30d)	-
Mar 31, 2020Mar 20 Reported Jun 3, 2020Reported Jun 3	$-3.30	$-2.13	-	-54.93%	Miss	-	-	-
Sep 30, 2019Sep 19 Reported Dec 6, 2019Reported Dec 6	$-0.06	$0.00	-	N/A	Miss	-	-	-
Jun 30, 2019Jun 19 Reported Sep 18, 2019Reported Sep 18	$-0.05	$0.00	-	N/A	Miss	-	-	-

Key Metrics

Valuation
P/E Ratio	-3.10	EV/EBITDA	N/A
Price/FCF	-3.75x	FCF Yield	-26.70%
Profitability
Profit Margin	0.00%	Operating Margin	0.00%
ROE	-105.30%	ROIC	N/A
Financial Health
Debt/Equity	0.00x	Interest Coverage	N/A
Current Ratio	5.53x	Quick Ratio	5.53x
Trading Statistics
Beta	1.33	Avg Volume	3.37M
52-Week High	$7.18	52-Week Low	$2.54

Technical Indicators Dashboard

Moving Averages

SMA 10$3.95

SMA 20$4.00

SMA 50$4.53

SMA 200$5.31

EMA 10$3.88

EMA 20$4.02

EMA 50$4.41

EMA 200$4.75

MACD

Line: -0.19Signal: -0.19Hist: -0.01

ADX

ADX: 21.1+DI: 14.2-DI: 30.8

Aroon & PSAR

Aroon Up60.0

Aroon Down100.0

PSAR$4.34

Bollinger Bands

Upper Band$4.40

Lower Band$3.59

%B Position2029%(Upper)

Band Width0.01

RSI (14-Day)

Neutral

31.0

Momentum Oscillators

Stoch %K14.1

Stoch %D26.8

Williams %R-89.7

ROC (10d)-12.6%

Momentum-0.52

CCI (20d)-159.6

MFI (14d)49.5

Volatility Measures

ATR (14d)$0.23(6.5%)

StdDev (20d)0.20

Hist Vol57.5%(High)

Volume Flow

VWAP$3.64

OBV22.5M

AD Line-47.8M

CMF (20d)-0.180

Volume Metrics

Avg Vol (20d)3.3M

Vol Ratio0.8x

VWMA (20d)$4.02

Pivot Points

R3$3.98

R2$3.92

R1$3.79

Pivot Point$3.73

S1$3.60

S2$3.54

S3$3.41

Advanced Oscillators

TSI-24.33

Ultimate Osc36.7

KST-116.80

Financial Data

Quarter	Jun 2026	Mar 2026	Dec 2025	Sep 2025	Jun 2025	Mar 2025	Dec 2024	Sep 2024	Jun 2024	Mar 2024	Dec 2023	Sep 2023
Total Revenue	$0	$0	$0	$0	$0	$0	$3.40M	$0	$0	$0	$4.87M	$0
Cost of Revenue	$0	$0	$945,000	$0	$0	$0	N/A	$0	$0	$0	$834,000	$0
Gross Profit	$0	$0	$-945,000	$0	$0	$0	$1.70M	$0	$0	$0	$4.03M	$0

Operating Expenses	$57.23M	$46.05M	$50.26M	$57.02M	$51.73M	$57.41M	$52.48M	$39.44M	$33.58M	$28.57M	$30.01M	$34.78M
R&D	$46.59M	$35.79M	$42.66M	$49.70M	$44.16M	$48.18M	$43.35M	$30.11M	$25.03M	$20.96M	$23.27M	$27.89M
SG&A	$10.64M	$10.27M	$7.60M	$7.32M	$7.57M	$9.23M	$9.13M	$9.34M	$8.55M	$7.61M	$6.74M	$6.89M
Operating Income	$-57,227,000	$-46,053,000	$-50,258,000	$-57,018,000	$-51,726,000	$-57,405,000	$-52,479,000	$-39,442,000	$-33,580,000	$-28,572,000	$-30,009,000	$-34,781,000

Interest Income	$1.88M	$1.91M	$2.00M	$2.10M	$2.57M	$3.05M	$3.89M	$4.62M	$3.97M	$3.40M	$2.12M	$2.30M
Interest Expense	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Income Before Tax	$-55,348,000	$-44,142,000	$-48,256,000	$-54,922,000	$-49,156,000	$-54,356,000	$-48,590,000	$-34,824,000	$-29,610,000	$-25,176,000	$-27,891,000	$-32,482,000
Income Tax Expense	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Net Income	$-55,348,000	$-44,142,000	$-48,256,000	$-54,922,000	$-49,156,000	$-54,356,000	$-48,590,000	$-34,824,000	$-29,610,000	$-25,176,000	$-27,891,000	$-32,482,000

EBITDA	$-56,946,000	$-46,146,000	$-50,139,000	$-56,947,000	$-52,442,000	$-58,718,000	$-54,964,000	$-42,004,000	$-34,838,000	$-29,171,000	$-29,731,000	$-34,838,000
EBIT	$-57,227,000	$-46,053,000	$-50,258,000	$-57,018,000	$-51,726,000	$-57,405,000	$-52,479,000	$-39,442,000	$-33,580,000	$-28,572,000	$-30,009,000	$-34,781,000

* Some calculated fields are derived from available data when not provided by source

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News

Annexon Price Target Raised to $15.00/Share From $14.00 by JP Morgan

JP Morgan has increased its price target for Annexon from $14.00 to $15.00 per share. This adjustment indicates a positive outlook from the financial institution regarding Annexon's future stock performance.

Moomoo•Sep 30, 2026 7:29 PM ET9/30/26•Bullish

JPMorgan raises Annexon Biosciences price target on trial data By Investing.com

JPMorgan increased its price target for Annexon Biosciences (NASDAQ:ANNX) to $15.00 from $14.00, maintaining an Overweight rating...

Investing.com Canada•Sep 30, 2026 10:29 AM ET9/30/26•Bullish

Insider Spends US$100k Buying More Shares In Annexon

Annexon's CEO, President & Director, Douglas Love, recently purchased US$100k worth of company stock. While this individual purchase signals confidence...

Simply Wall Street•Sep 27, 2026 6:22 PM ET9/27/26•Somewhat-Bullish

Annexon (ANNX) President and CEO Douglas Love Buys 26,065 Shares

Douglas Love, President and CEO of Annexon Inc (ANNX), recently purchased 26,065 shares of the company on September 24, 2026, increasing his total holdings to 390,476 shares. The transaction, valued at $3.83 per share...

GuruFocus•Sep 26, 2026 11:19 AM ET9/26/26•Bullish

After buying shares at a $3.83 average, Annexon (ANNX) CEO Love Douglas holds 390,476 shares.

Annexon, Inc. President and CEO Love Douglas purchased 26,065 shares of common stock on September 24, 2026, at a weighted average price of $3.83 per share, bringing his direct holdings to 390,476 shares. The transaction...

Stock Titan•Sep 25, 2026 4:19 PM ET9/25/26•Bullish

ANNX Valuation and Fair Value

P/E: -3.1x
P/FCF: -3.7x
P/B: 3.9x

See GNG's fair value

ANNX Profitability: Margins, ROIC and FCF

Operating margin: 0.0%
Net margin: 0.0%
ROE: -105.3%
FCF yield: -26.7%

ANNX Competitors

Company	Ticker
Sana Biotechnology Inc	SANA
Gyre Therapeutics Inc.	GYRE
Verastem Inc	VSTM
MiMedx Group Inc	MDXG
Adlai Nortye Ltd. American Depositary Shares	ANL
Design Therapeutics Inc	DSGN
Collegium Pharmaceutical Inc	COLL
Inventiva Sa	IVA

Sector: Healthcare

ANNX Analyst Ratings

Consensus: Buy
Analysts: 10
Strong Buy: 2
Buy: 6
Hold: 2
Sell: 0
Strong Sell: 0

ANNX Bull Case vs Bear Case

Bull case

80.0% of ANNX's analyst ratings are Buy or Strong Buy.

ANNX Earnings: Beat Rate and Next Report

Beat rate: 4 of 8 quarters (50.0%)
Average surprise: -2.7%
EPS estimate (fiscal period ending Sep 30, 2026): $-0.28
Estimate revisions (30 days, fiscal period ending Sep 30, 2026): 0 up, 5 down

Frequently Asked Questions About ANNX

Does ANNX pay dividends?

Annexon Inc (ANNX) does not currently pay a regular dividend.

What is ANNX's market cap?

Annexon Inc (ANNX) has a market capitalization of $695.75M with a current stock price of $3.60.

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